Five Articles from HealZen Therapeutics have been Selected for the 64th American Society of Hematology (ASH) Annual Meeting (New Orleans, USA)

TIME:

Dec 03,2022

ASH is one of the world's top-level international hematology conferences and attracts tens of thousands of experts and scholars engaged in clinical and basic research in the field of hematology from all over the world every year. ASH focuses on the latest developments and hot topics in the field, leading the direction of international development. 
The 64th ASH Annual Conference will be held in New Orleans, USA from December 10th to 13th this year. After being reviewed by international authoritative experts, a total of 3 Posters and 2 Publications from HealZen were selected for the ASH conference.

3 Posters
Abstract: 2157

Title: Discovery and Preclinical Study of Novel BTK Degrader HZ-Q1060
Session Name: 802. Chemical Biology and Experimental Therapeutics: Poster I
Session Date: Saturday, December 10, 2022
Presentation Time: 5:30 PM - 7:30 PM
Presenting Author: Xingguo Liu, Yubo Zhou, Yizhe Wu, Xiaomin Luo, Jiangfeng Xie, Xinxin Jin, Haiyan Yang, Jia Li, Xinglu Zhou
Abstract: 3472
Title: Discovery of HZ-L105, a Next Generation of Bcl-2 Inhibitor, Overcomes Bcl-2 Mutation and Exhibits Superior Antitumor Activity
Session Name: 802. Chemical Biology and Experimental Therapeutics: Poster II
Session Date: Sunday, December 11, 2022
Presentation Time: 6:00 PM - 8:00 PM
Presenting Author: Xingguo Liu, Yang Lou, Yizhe Wu, MingBo Su, AnHui Gao, Jinglai Huang, Haiyan Yang, Li Zhong, Xinglu Zhou
Abstract:3482
Title: HZ-R061, a Selective STAT3 Degrader with Activity in Preclinical Model of Hematologic Malignances
Session Name: 802. Chemical Biology and Experimental Therapeutics: Poster III
Session Date: Sunday, December 11, 2022
Presentation Time: 6:00 PM - 8:00 PM
Presenting Author: Yizhe Wu, Xingguo Liu, Xinxin Jin, Jiangfeng Xie, Haiyan Yang, Xinglu Zhou


2 Publications
Abstract:5501

Title: HZ-A-018 Is a Highly Selective and Potent BTK Inhibitor with CNS-Penetrating Profile for Central Nervous System Lymphoma
Presenting Author: Zhuang Kang, Feng Chen, Yi Lin, Xianggui Yuan, Xi Chen, Wenbin Qian, Haiyan Yang, Miao Hu, Xingguo Liu, Xinglu Zhou, Wenbin Li
Abstract:5502
Title: Dual CK1ε/PI3Kδ Inhibitor HZ-H08905, Exhibits As a Potential Therapeutic Strategy for Hematologic Malignancies
Presenting Author: Juying Wei, Wenjuan Yu, Hongyan Tong, Min Yang, Miao Hu, Xingguo Liu, Yizhe Wu, Xinglu Zhou, Jie Jin

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